The history of wine in Tuscany was born a long time ago.Viticulture in Tuscany has a thousand-year history, deep and rooted throughout the region: it is said that as early as 500 BC. the ancient Etruscans produced wine in present-day Tuscany.. Sangiovese is the king of grapes in Tuscany and is used in most of the different regional appellations. Often, you can find Sangiovese in blends with other local varieties such as Canaiolo, Colorino, or Ciliegiolo or with international grapes such as Cabernet Sauvignon or Merlot. Tuscany is home to 11 regions bearing the label Denominazione di Origine Controllata e Garantita (DOCGs) and 42 designated as Denominazione di Origine Controllata (DOCs).